Tramadol is a synthetic opioid used to manage moderate to severe pain. It works by binding to receptors in the brain and spinal cord to alter the body's perception of pain . Tramadol is available in immediate-release and extended-release formulations and can be administered orally in tablet or solution form once every four to six hours, depending upon the formulation used . Like other opioid medications, tramadol carries a risk of addiction, abuse, and overdose .